DMS (Derma Membrane Structure)

DMS is an abbreviation of the term derma membrane structure. The special feature of DMS consists in the fact that its structure is very similar to the horny layers of the skin barrier and with regard to its chemical structure, it is related to the natural components of the skin. This concept consequently avoids additives like emulsifiers, perfumes, mineral oils, silicones and emulsifiers which are used in conventional products.

Just like liposomes and nanoparticles, DMS bases cannot be produced by using conventional emulsifying technologies. The manufacturing process requires a specific high-pressure homogenization procedure and in many cases this process has to be run repeatedly.
When the DMS structure finally is built up, it acts like the skin barrier layers: it has the capacity of assimilating hydrophilic and lipophilic substances which happens e.g. in the pharmacy by simply stirring in these agents at room temperature. Generally, it can be stated that the creams produced by means of the above described procedure are physically very stable so that a minimum shelf life of 6 to 12 months can easily be guaranteed.

The DMS is part of the membrane family. In contrast to liposomes and nanoparticles which consist of native PC (its fatty acid population mainly is linoleic acid), the DMS contains a hydrogenated PC (with a fatty acid population of stearic acid and palmitic acid) which shows ceramide-like properties. Hence, hydrogenated PC has a high natural affinity to the lipid bilayers of the skin barrier, stabilizes the trans-epidermal water loss in a physiologically useful balance and protects the skin against the penetration of foreign substances. As it does not impede the natural skin regeneration, but on the contrary simultaneously rather supports it, it is meanwhile being used in the field of occupational skin protection1).

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